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Series Preface... Foreword... Preface... Table of Contents... Contributing Authors... Part I Models for Seizures and Epilepsy: An Overview 1. Models of Seizures and Epilepsy: Important Tools in the Discovery and Evaluation of Novel Epilepsy Therapies Wolfgang Löscher Part II Ex Vivo and In Vitro Models 2. Protocol for Rodent Organotypic Hippocampal Slice Culture Model for Ex Vivo Monitoring of Epileptogenesis Shabnam Ghiasvand, Jing Liu, Md. Joynal Abedin, and Yevgeny Berdichevsky 3. Methods for the Screening of New Chemical Entities for Deciphering Neuroinflammatory and Associated Pathways in Seizures: An In Vitro Perspective Preeti Vyas, Rajkumar Tulsawani, and Divya Vohora 4. Cellular Electrophysiological Methods to Decipher the Altered Synaptic Transmission Associated with Drug Resistant Epilepsy Soumil Dey, Aparna Banerjee Dixit, Manjari Tripathi, P. Sarat Chandra, and Jyotirmoy Banerjee Part III In Vivo Rodent Models 5. Acute Seizure Tests Used in Epilepsy Research: Step-by-Step Protocol of the Maximal Electroshock Seizure (MES) Test, The Maximal Electroshock Seizure Threshold (MEST) Test, and the Pentylenetetrazole (PTZ)-Induced Seizure Test in Rodents Katarzyna Socala and Piotr Wlaz 6. Procedures for Electrical and Chemical Kindling Models in Rats and Mice Heidrun Potschka 7. Methods for the Induction of status epilepticus and Temporal Lobe Epilepsy in Rodents: The Kainic Acid and the Pilocarpine Model Shreshta Jain, Nikita Nirwan, Fahim H. Pottoo, Nidhi Bharal Agarwal, and Divya Vohora 8. Seizure Monitoring in Rodents Edward H. Bertram Part IV Models for Refractory Seizures 9. Protocol for 6Hz Corneal Stimulation in Rodents for Refractory Seizures Razia Khanam and Divya Vohora 10. A Method to Induce Lamotrigine-Resistant Corneal Kindled Mice Melissa Barker-Haliski 11. Protocol for Drug Screening with Quantitative Video-Electroencephalography in a Translational Model of Refractory Neonatal Seizures Brennan J. Sullivan and Shilpa D. Kadam Part V Invertebrate/Non-Mammalian Models 12. Methods to Investigate Seizures and Associated Cognitive Decline using Zebrafish Model Brandon Choo Kar Meng and Mohd. Farooq Shaikh 13. C. elegans as a Potential Model for Acute Seizure-Like Activity Alistair Jones, Anthony G. Marson, Vincent T. Cunliffe, Graeme J. Sills, and Alan Morgan Subject Index List...
Series Preface... Foreword... Preface... Table of Contents... Contributing Authors... Part I Models for Seizures and Epilepsy: An Overview 1. Models of Seizures and Epilepsy: Important Tools in the Discovery and Evaluation of Novel Epilepsy Therapies Wolfgang Löscher Part II Ex Vivo and In Vitro Models 2. Protocol for Rodent Organotypic Hippocampal Slice Culture Model for Ex Vivo Monitoring of Epileptogenesis Shabnam Ghiasvand, Jing Liu, Md. Joynal Abedin, and Yevgeny Berdichevsky 3. Methods for the Screening of New Chemical Entities for Deciphering Neuroinflammatory and Associated Pathways in Seizures: An In Vitro Perspective Preeti Vyas, Rajkumar Tulsawani, and Divya Vohora 4. Cellular Electrophysiological Methods to Decipher the Altered Synaptic Transmission Associated with Drug Resistant Epilepsy Soumil Dey, Aparna Banerjee Dixit, Manjari Tripathi, P. Sarat Chandra, and Jyotirmoy Banerjee Part III In Vivo Rodent Models 5. Acute Seizure Tests Used in Epilepsy Research: Step-by-Step Protocol of the Maximal Electroshock Seizure (MES) Test, The Maximal Electroshock Seizure Threshold (MEST) Test, and the Pentylenetetrazole (PTZ)-Induced Seizure Test in Rodents Katarzyna Socala and Piotr Wlaz 6. Procedures for Electrical and Chemical Kindling Models in Rats and Mice Heidrun Potschka 7. Methods for the Induction of status epilepticus and Temporal Lobe Epilepsy in Rodents: The Kainic Acid and the Pilocarpine Model Shreshta Jain, Nikita Nirwan, Fahim H. Pottoo, Nidhi Bharal Agarwal, and Divya Vohora 8. Seizure Monitoring in Rodents Edward H. Bertram Part IV Models for Refractory Seizures 9. Protocol for 6Hz Corneal Stimulation in Rodents for Refractory Seizures Razia Khanam and Divya Vohora 10. A Method to Induce Lamotrigine-Resistant Corneal Kindled Mice Melissa Barker-Haliski 11. Protocol for Drug Screening with Quantitative Video-Electroencephalography in a Translational Model of Refractory Neonatal Seizures Brennan J. Sullivan and Shilpa D. Kadam Part V Invertebrate/Non-Mammalian Models 12. Methods to Investigate Seizures and Associated Cognitive Decline using Zebrafish Model Brandon Choo Kar Meng and Mohd. Farooq Shaikh 13. C. elegans as a Potential Model for Acute Seizure-Like Activity Alistair Jones, Anthony G. Marson, Vincent T. Cunliffe, Graeme J. Sills, and Alan Morgan Subject Index List...
Models of Seizures and Epilepsy: Important Tools in the Discovery and Evaluation of Novel Epilepsy Therapies .- Protocol for Rodent Organotypic Hippocampal Slice Culture Model for Ex Vivo Monitoring of Epileptogenesis.- Methods for the Screening of New Chemical Entities for Deciphering Neuroinflammatory and Associated Pathways in Seizures: An In Vitro Perspective.- Cellular Electrophysiological Methods to Decipher the Altered Synaptic Transmission Associated with Drug Resistant Epilepsy.- Acute Seizure Tests Used in Epilepsy Research: Step-by-Step Protocol of the Maximal Electroshock Seizure (MES) Test, The Maximal Electroshock Seizure Threshold (MEST) Test, and the Pentylenetetrazole (PTZ)-Induced Seizure Test in Rodents.- Procedures for Electrical and Chemical Kindling Models in Rats and Mice.- Methods for the Induction of status epilepticus and Temporal Lobe Epilepsy in Rodents: The Kainic Acid and the Pilocarpine Model.- Seizure Monitoring inRodents.- Protocol for 6Hz Corneal Stimulation in Rodents for Refractory Seizures.- A Method to Induce Lamotrigine-Resistant Corneal Kindled Mice.- Protocol for Drug Screening with Quantitative Video-Electroencephalography in a Translational Model of Refractory Neonatal Seizures.- Methods to Investigate Seizures and Associated Cognitive Decline using Zebrafish Model.- C. elegans as a Potential Model for Acute Seizure-Like Activity.
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