Table of Contents

Contents

Foreword by Joseph G. McCarthy XXX

Preface to the Third Edition XXX

List of Contributors XXX

Acknowledgments XXX

Dedication XXX

Volume One: Principles

Geoffrey C. Gurtner

1 Plastic surgery and innovation in medicine XXXPeter C. Neligan

2 History of reconstructive and aesthetic surgery XXXRiccardo F. Mazzola and Isabella C. Mazzola

3 Psychological aspects of plastic surgery XXXLaurie A. Stevens and Mary H. McGrath

4 The role of ethics in plastic surgery XXXPhillip C. Haeck

5 Business principles for plastic surgeons XXXC. Scott Hultman

6 Medico-legal issues in plastic surgery XXXNeal R. Reisman

7 Photography in plastic surgery XXXBrian M. Kinney

8 Patient safety in plastic surgery XXXBruce Halperin

9 Local anesthetics in plastic surgery XXXA. Aldo Mottura

10 Evidence-based medicine and health services research in plastic surgery XXXCarolyn L. Kerrigan, E. Dale Collins Vidal, Andrea L. Pusic, Amy K. Alderman, and Valerie Lemaine

11 Genetics and prenatal diagnosis XXXDaniel Nowinski, Elizabeth Kiwanuka, Florian Hackl, Bohdan Pomahac, and Elof Eriksson

12 Principles of cancer management XXXTomer Avraham, Evan Matros, and Babak J. Mehrara

13 Stem cells and regenerative medicine XXXBenjamin Levi, Derrick C. Wan, Victor W. Wong, Geoffrey C. Gurtner, and Michael T. Longaker

14 Wound healing XXXChandan K. Sen and Sashwati Roy

15 Skin wound healing: Repair biology, wound, and scar treatment XXXUrsula Mirastschijski, Andreas Jokuszies, and Peter M. Vogt

16 Scar prevention, treatment, and revision XXXPeter Lorenz and A. Sina Bari

17 Skin graft XXXSaja S. Scherer-Pietramaggiori, Giorgio Pietramaggiori, and Dennis P. Orgill

18 Tissue graft, tissue repair, and regeneration XXXWei Liu and Yilin Cao

19 Tissue engineering XXXAndrea J. O'Connor and Wayne A. Morrison

20 Repair, grafting, and engineering of cartilage XXXWei Liu and Yilin Cao

21 Repair and grafting of bone XXXIris A. Seitz, Chad M. Teven, and Russell R. Reid

22 Repair and grafting of peripheral nerve XXXRenata V. Weber, Kirsty U. Boyd, and Susan E. Mackinnon

23 Vascular territories XXXSteven F. Morris and G. Ian Taylor

24 Flap classification and applications XXXScott L. Hansen, David M. Young, Patrick Lang, and Hani Sbitany

25 Flap pathophysiology and pharmacology XXXCho Y. Pang and Peter C. Neligan

26 Principles and techniques of microvascular surgery XXXFu-Chan Wei and Sherilyn Keng Lin Tay

27 Principles and applications of tissue expansion XXXMalcolm W. Marks and Louis C. Argenta

28 Therapeutic radiation: Principles, effects, and complications XXXGabrielle M. Kane

29 Vascular anomalies XXXArin K. Greene and John B. Mulliken

30 Benign and malignant nonmelanocytic tumors of the skin and soft tissue XXXRei Ogawa

31 Melanoma XXXStephan Ariyan and Aaron Berger

32 Implants and biomaterials XXXCharles E. Butler and Timothy W. King

33 Facial prosthetics in plastic surgery XXXGordon H. Wilkes, Mohammed M. Al Kahtani, and Johan F. Wolfaardt

34 Transplantation in plastic surgery XXXDavid W. Mathes, Peter E. M. Butler, and W. P. Andrew Lee

35 Technology innovation in plastic surgery: A practical guide for the surgeon innovator XXXLeila Jazayeri and Geoffrey C. Gurtner

36 Robotics, simulation, and telemedicine in plastic surgery XXXJoseph M. Rosen, Todd E. Burdette, Erin Donaldson, Robyn Mosher, Lindsay B. Katona, and Sarah A. Long

Volume Two: Aesthetic

Richard J. Warren

1 Managing the cosmetic patient XXXMichelle B. Locke and Foad Nahai

Section I: Aesthetic Surgery of the Face

2 Nonsurgical skin care and rejuvenation XXXLeslie Baumann

3 Botulinum toxin (BoNT-A) XXXMichael A.C. Kane

4 Soft-tissue fillers XXXTrevor M. Born, Lisa E. Airan, and Dimitrios Motakis

5 Facial skin resurfacing XXXSteven R. Cohen, Ryan C. Frank, and E. Victor Ross

6 Anatomy of the aging face XXXBryan Mendelson and Chin-Ho Wong

7 Forehead rejuvenation XXXRichard J. Warren

8 Blepharoplasty XXXJulius Few Jr. and Marco Ellis

9 Secondary blepharoplasty: Techniques XXXGlenn W. Jelks, Elizabeth B. Jelks, Ernest S. Chiu, and Douglas S. Steinbrech

10 Asian facial cosmetic surgery XXXKyung S. Koh, Jong Woo Choi, and Clyde H. Ishii

11.1 Facelift: Principles XXXRichard J. Warren

11.2 Facelift: Introduction to deep tissue techniques XXXRichard J. Warren

11.3 Facelift: Platysma-SMAS plication XXXDai M. Davies and Miles G. Berry

11.4 Facelift: Facial rejuvenation with loop sutures, the MACS lift and its derivatives XXXMark Laurence Jewell

11.5 Facelift: Lateral SMASectomy XXXDaniel C. Baker

11.6 Facelift: The extended SMAS technique in facial rejuvenation XXXJames M. Stuzin

11.7 Facelift: SMAS with skin attached - the "high SMAS" technique XXXFritz E. Barton Jr.

11.8 Facelift: Subperiosteal facelift XXXOscar M. Ramirez

12 Secondary deformities and the secondary facelift XXXTimothy J. Marten and Dino Elyassnia

13 Neck rejuvenation XXXJames E. Zins, Colin Myles Morrison, and Claude-Jean Langevin

14 Structural fat grafting XXXSydney R. Coleman and Alesia P. Saboeiro

15 Skeletal augmentation XXXMichael J. Yaremchuk

16 Anthropometry, cephalometry, and orthognathic surgery XXXDaniel I. Taub, Jordan M.S. Jacobs, and Jonathan S. Jacobs

17 Nasal analysis and anatomy XXXJoel E. Pessa and Rod J. Rohrich

18 Open technique rhinoplasty XXXRod J. Rohrich and Jamil Ahmad

19 Closed technique rhinoplasty XXXMark B. Constantian

20 Airway issues and the deviated nose XXXBahman Guyuron and Bryan S. Armijo

21 Secondary rhinoplasty XXXRonald P. Gruber, Simeon H. Wall Jr., David L. Kaufman, and David M. Kahn

22 Otoplasty XXXCharles H. Thorne

23 Hair restoration XXXJack Fisher

Section II: General Aesthetic Surgery

24 Liposuction: A comprehensive review of techniques and safety XXXJeffrey M. Kenkel and Phillip J. Stephan

25 Abdominoplasty procedures XXXDirk F. Richter and Alexander Stoff

26 Lipoabdominoplasty XXXOsvaldo Ribeiro Saldanha, S�rgio Fernando Dantas de Azevedo, Osvaldo Ribeiro Saldanha Filho, Cristianna Bonneto Saldanha, and Luis Humberto Uribe Morelli

27 Lower bodylifts XXXAl Aly, Khalid Al-Zahrani, and Albert Cram

28 Buttock augmentation XXXTerrence W. Bruner, Jos� Abel de la Pe�a Salcedo, Constantino G. Mendieta, and Thomas L. Roberts III

29 Upper limb contouring XXXJoseph F. Capella, Matthew J. Trovato, and Scott Woehrle

30 Post-bariatric reconstruction XXXJonathan W. Toy and J. Peter Rubin

31 Aesthetic genital surgery XXXGary J. Alter

Volume Three: Craniofacial, Head and Neck Surgery and Pediatric Plastic Surgery

Part 1: Craniofacial, head and neck surgery: Eduardo D. Rodriguez

1 Anatomy of the head and neck XXXAhmed M. Afifi and Risal Djohan

Section I: Craniofacial Trauma

2 Facial trauma: Soft tissue injuries XXXReid V. Mueller

3 Facial fractures XXXEduardo D. Rodriguez, Amir H. Dorafshar, and Paul N. Manson

4 TMJ dysfunction and obstructive sleep apnea XXXStephen A. Schendel and Brinda Thimmappa

Section II: Head and Neck Reconstruction

5 Scalp and forehead reconstruction XXXMark D. Wells and Carla Skytta

6 Aesthetic nasal reconstruction XXXFrederick J. Menick

7 Reconstruction of the ear XXXBurton D. Brent

8 Acquired cranial and facial bone deformities XXXRenee M. Burke, Robert J. Morin, and S. Anthony Wolfe

9 Midface reconstruction XXXConstance M. Chen, Joseph J. Disa, and Peter G. Cordeiro

10 Cheek and lip reconstruction XXXPeter C. Neligan

11 Facial paralysis XXXRonald M. Zuker, Eyal Gur, Gazi Hussain, and Ralph T. Manktelow

12 Oral cavity, tongue, and mandibular reconstructions XXXMing-Huei Cheng and Jung-Ju Huang

13 Hypopharyngeal, esophageal, and neck reconstruction XXXPeirong Yu

14 Salivary gland tumors XXXStephan Ariyan, Deepak Narayan, and Charlotte E. Ariyan

15 Tumors of the facial skeleton: Fibrous dysplasia XXXYou-Wei Cheong and Yu-Ray Chen

16 Tumors of the lips, oral cavity, oropharynx, and mandible XXXJohn Joseph Coleman III and Anthony P. Tufaro

17 Carcinoma of the upper aerodigestive tract XXXMichael E. Kupferman, Justin M. Sacks, and Edward I. Chang

18 Local flaps for facial coverage XXXIan T. Jackson

19 Secondary facial reconstruction XXXJulian J. Pribaz and Rodney K. Chan

20 Facial transplant XXXLaurent Lantieri

21 Surgical management of migraine headaches XXXBahman Guyuron and Ali Totonchi

Part 2: Pediatric plastic surgery: Joseph E. Losee

Section I: Clefts

22 Embryology of the craniofacial complex XXXMaryam Afshar, Samantha A. Brugmann, and Jill A. Helms

23 Repair of unilateral cleft lip XXXPhilip Kuo-Ting Chen, M. Samuel Noordhoff, and Alex Kane

24 Repair of bilateral cleft lip XXXJohn B. Mulliken

25 Cleft palate XXXWilliam Y. Hoffman

26 Alveolar clefts XXXRichard A. Hopper

27 Orthodontics in cleft lip and palate management XXXAlvaro A. Figueroa and John W. Polley

28 Velopharyngeal dysfunction XXXRichard E. Kirschner and Adriane L. Baylis

29 Secondary deformities of the cleft lip, nose, and palate XXXEvan M. Feldman, John C. Koshy, Larry H. Hollier Jr., and Samuel Stal

30 Cleft and craniofacial orthognathic surgery XXXJesse A. Goldstein and Steven B. Baker

Section II: Craniofacial

31 Pediatric facial fractures XXXJoseph E. Losee and Darren M. Smith

32 Orbital hypertelorism XXXEric Arnaud, Daniel Marchac, Federico Di Rocco, and Dominique Renier

33 Craniofacial clefts XXXJames P. Bradley and Henry K. Kawamoto Jr.

34 Nonsyndromic craniosynostosis XXXDerek M. Steinbacher and Scott P. Bartlett

35 Syndromic craniosynostosis XXXJeffrey A. Fearon

36 Craniofacial microsomia XXXJoseph G. McCarthy, Barry H. Grayson, Richard A. Hopper, and Oren M. Tepper

37 Hemifacial atrophy XXXPeter J. Taub, Lester Silver, and Kathryn S.Torok

38 Pierre Robin sequence XXXChristopher G. Zochowski and Arun K. Gosain

39 Treacher-Collins syndrome XXXFernando Molina

Section III: Pediatrics

40 Congenital melanocytic nevi XXXBruce S. Bauer and Neta Adler

41 Pediatric chest and trunk defects XXXLawrence J. Gottlieb, Russell R. Reid, and Justine C. Lee

42 Pediatric tumors XXXSahil Kapur and Michael L. Bentz

43 Conjoined twins XXXOksana Jackson, David W. Low and Don LaRossa

44 Reconstruction of urogenital defects: Congenital XXXMohan S. Gundeti and Michael C. Large

Volume Four: Lower Extremity, Trunk and Burns

David Song

Section I: Lower Extremity Surgery

1 Comprehensive lower extremity anatomy XXXGinard I. Henry and Grant M. Kleiber

2 Management of lower extremity trauma XXXShannon Colohan and Michel Saint-Cyr

3 Lymphatic reconstruction of the extremities XXXRuediger G. H. Baumeister, David W. Chang, and Peter C. Neligan

4 Lower extremity sarcoma reconstruction XXXGoetz A.Giessler and Michael Sauerbier

5 Reconstructive surgery: Lower extremity coverage XXXJoon Pio Hong

6 Diagnosis and treatment of painful neuroma and of nerve compression in the lower extremity XXXA. Lee Dellon

7 Skeletal reconstruction XXXStephen J. Kovach and L. Scott Levin

8 Foot reconstruction XXXMark W. Clemens, Lawrence B. Colen, and Christopher E. Attinger

Section II: Trunk Surgery

9 Comprehensive trunk anatomy XXXMichael A. Howard and Sara R. Dickie

10 Reconstruction of the chest XXXDavid H. Song and Michelle C. Roughton

11 Reconstruction of the soft tissues of the back XXXGregory A. Dumanian

12 Abdominal wall reconstruction XXXNavin K. Singh, Marwan R. Khalifeh, and Jonathan Bank

13 Reconstruction of male genital defects XXXStan Monstrey, Peter Ceulemans, Nathalie Roche, Philippe Houtmeyers, Nicolas Lumen, and Piet Hoebeke

14 Reconstruction of acquired vaginal defects XXXLaura Snell, Peter G. Cordeiro, and Andrea L. Pusic

15 Surgery for gender identity disorder XXXLoren S. Schechter

16 Pressure sores XXXRobert Kwon and Jeffrey E. Janis

17 Perineal reconstruction XXXHakim K. Said and Otway Louie

Section III: Burns Surgery

18 Acute management of burn/electrical injuries XXXLars Steinstraesser and Sammy Al-Benna

19 Extremity burn reconstruction XXXLorenzo Borghese, Alessandro Masellis, and Michele Masellis

20 Cold and chemical injury to the upper extremity XXXDennis S. Kao and John Hijjawi

21 Management of facial burns XXXRobert J. Spence

22 Reconstructive burn surgery XXXMatthew B. Klein

23 Management of patients with exfoliative disorders, epidermolysis bullosa, and TEN XXXAbdullah E. Kattan, Robert C. Cartotto, and Joel S. Fish

Volume Five: Breast

James C. Grotting

1 Anatomy for plastic surgery of the breast XXXJorge I. de la Torre and Michael R. Davis

Section I: Cosmetic Surgery of the Breast

2 Breast augmentation XXXG. Patrick Maxwell and Allen Gabriel

3 Secondary breast augmentation XXXMitchell H. Brown

4 Current concepts in revisionary breast surgery XXXG. Patrick Maxwell and Allen Gabriel

5 Endoscopic approaches to the breast XXXNeil A. Fine and Clark F. Schierle

6 Iatrogenic disorders following breast surgery XXXWalter Peters

7 Mastopexy XXXKent K. Higdon and James C. Grotting

8.1 Reduction mammaplasty XXXJack Fisher and Kent K. Higdon

8.2 Inferior pedicle breast reduction XXXJack Fisher

8.3 Superior or medial pedicle XXXFrank Lista and Jamil Ahmad

8.4 Short scar periareolar inferior pedicle reduction (SPAIR) mammaplasty XXXDennis C. Hammond

8.5 The L short-scar mammaplasty XXXArmando Chiari Jr.

8.6 Periareolar technique with mesh support XXXJoao Carlos Sampaio G�es

8.7 Sculpted pillar vertical reduction mammaplasty XXXKent K. Higdon and James C. Grotting

9 Revision surgery following breast reduction and mastopexy XXXKenneth C. Shestak

Section II: Reconstructive Surgery of the Breast

10 Breast cancer: Diagnosis therapy and oncoplastic techniques XXXElisabeth Beahm and Julie E. Lang

11 The oncoplastic approach to partial breast reconstruction XXXAlbert Losken

12 Patient-centered health communication XXXGary L. Freed, Alice Andrews, and E. Dale Collins Vidal

13 Imaging in reconstructive breast surgery XXXJaume Masia, Carmen Navarro, and Juan A. Clavero

14 Expander-implants breast reconstruction XXXMaurizio B. Nava, Giuseppe Catanuto, Angela Pennati, Valentina Visintini Cividin, and Andrea Spano

15 Latissimus dorsi flap breast reconstruction XXXScott L. Spear and Mark W. Clemens

16 The bilateral pedicled TRAM flap XXXL. Franklyn Elliott, John D. Symbas, and Hunter R. Moyer

17 Free TRAM breast reconstruction XXXJoshua Fosnot and Joseph M. Serletti

18 The deep inferior epigastric artery perforator (DIEAP) flap XXXPhillip N. Blondeel, Colin M. Morrison, and Robert J. Allen

19 Alternative flaps for breast reconstruction XXXMaria M. LoTempio, Robert J. Allen, and Phillip N. Blondeel

20 Omentum reconstruction of the breast XXXJoao Carlos Sampaio G�es and Antonio Luiz Vasconcellos Macedo

21 Local flaps in partial breast reconstruction XXXMoustapha Hamdi and Eugenia J. Kyriopoulos

22 Reconstruction of the nipple-areola complex XXXKetan M. Patel and Maurice Y. Nahabedian

23.1 Congenital anomalies of the breast XXXEgle Muti

23.2 Poland syndrome XXXPietro Berrino and Valeria Berrino

24 Contouring of the arms, breast, upper trunk, and male chest in the massive weight loss patient XXXJonathan W. Toy and J. Peter Rubin

25 Fat grafting to the breast XXXHenry Wilson and Scott L. Spear

Volume Six: Hand and Upper Extremity

James Chang

Introduction: Plastic surgery contributions to hand surgery xxxvii

James Chang

Section I: Introduction and Principles

1 Anatomy and biomechanics of the hand XXXJames Chang, Francisco Valero-Cuevas, Vincent R. Hentz, and Robert A. Chase

2 Examination of the upper extremity XXXRyosuke Kakinoki

3 Diagnostic imaging of the hand and wrist XXXAlphonsus K. Chong and David M.K. Tan

4 Anesthesia for upper extremity surgery XXXJonay Hill, Vanila M. Singh and Subhro K. Sen

5 Principles of internal fixation as applied to the hand and wrist XXXJeffrey Yao and Christopher Cox

Section II: Acquired Traumatic Disorders

6 Nail and fingertip reconstruction XXXMichael W. Neumeister, Elvin G. Zook, Nicole Z. Sommer, and Theresa A. Hegge

7 Hand fractures and joint injuries XXXWarren C. Hammert

8 Fractures and dislocations of the wrist and distal radius XXXKevin C. Chung and Steven C. Haase

9 Flexor tendon injury and reconstruction XXXJin Bo Tang

10 Extensor tendon injuries XXXKai Megerle and G�nther Germann

11 Replantation and revascularization XXXWilliam W. Dzwierzynski

12 Reconstructive surgery of the mutilated hand XXXWilliam C. Pederson and Randolph Sherman

13 Thumb reconstruction: Nonmicrosurgical techniques XXXNicholas B. Vedder and Jeffrey B. Friedrich

14 Thumb and finger reconstruction: Microsurgical techniques XXXFu Chan Wei and Wee Leon Lam

Section III: Acquired Nontraumatic Disorders

15 Benign and malignant tumors of the hand XXXJustin M. Sacks, Kodi K. Azari, Scott Oates, and David W. Chang

16 Infections of the hand XXXSean M. Bidic and Tim Schaub

17 Management of Dupuytren's disease XXXAndrew J. Watt and Caroline Leclercq

18 Occupational hand disorders XXXSteven J. McCabe

19 Rheumatologic conditions of the hand and wrist XXXDouglas M. Sammer and Kevin C. Chung

20 Osteoarthritis in the hand and wrist XXXBrian T. Carlsen, Karim Bakri, Faisal M. Al-Mufarrej and Steven L. Moran

21 The stiff hand and the spastic hand XXXDavid T. Netscher

22 Ischemia of the hand XXXHee Chang Ahn and Neil F. Jones

23 Complex regional pain syndrome in the upper extremity XXXIvica Ducic and John M. Felder III

24 Nerve entrapment syndromes XXXMichael Bezuhly, James P. O'Brien and Donald Lalonde

Section IV: Congenital Disorders

25 Congenital hand I: Embryology, classification, and principles XXXMichael Tonkin and Kerby Oberg

26 Congenital hand II: Disorders of formation (transverse and longitudinal arrest) XXXGill Smith and Paul Smith

27 Congenital hand III: Disorders of formation - thumb hypoplasia XXXJoseph Upton III and Amir Taghinia

28 Congenital hand IV: Disorders of differentiation and duplication XXXSteven E.R. Hovius

29 Congenital hand V: Disorders of overgrowth, undergrowth, and generalized skeletal deformities XXXLeung Kim Hung, Ping Chung Leung, and Takayuki Miura (Addendum by Michael Tonkin)

30 Growth considerations in pediatric upper extremity trauma and reconstruction XXXMarco Innocenti and Carla Baldrighi

31 Vascular anomalies of the upper extremity XXXJoseph Upton III

Section V: Paralytic Disorders

32 Peripheral nerve injuries of the upper extremity XXXSimon Farnebo, Johan Thorfinn, and Lars B. Dahlin

33 Nerve transfers XXXKirsty U. Boyd, Ida K. Fox, and Susan E. Mackinnon

34 Tendon transfers in the upper extremity XXXNeil F. Jones

35 Free-functioning muscle transfer in the upper extremity XXXIsaac Harvey and Gregory H. Borschel

36 Brachial plexus injuries: Adult and pediatric XXXDavid Chwei-Chin Chuang

37 Restoration of upper extremity function in tetraplegia XXXCatherine Curtin and Vincent R. Hentz

Section VI: Rehabilitation

38 Upper extremity composite allotransplantation XXXVijay S. Gorantla, Stefan S. Schneeberger, and W.P. Andrew Lee

39 Hand therapy XXXChristine B. Novak and Rebecca L. von der Heyde

40 Treatment of the upper extremity amputee XXXGregory A. Dumanian and Todd A. Kuiken

Index to all volumes iXXX-iXXX

About the Author

Peter Neligan, MB, FRCS, FRCSC, FAC., is a board-certified plastic surgeon, Director of the Center for Reconstructive Surgery at UW Medical Center - Montlake, and a Professor of Surgery in the Division of Plastic Surgery at UW School of Medicine. Dr. Neligan specializes in reconstructive surgery including flap surgery, lymphatic surgery, facial re-animation and facial transplantation.. He strives to provide the best care for patients and provide them with the best treatments available. He is excited by new techniques and solutions and always tries to improve every aspect of care. Dr. Neligan has authored four books, 180 scientific papers, 75 book chapters, edited 10 textbooks and is editor-in-chief of the Journal for Reconstructive Microsurgery. He is president of the Plastic Surgery Foundation, a member of multiple professional organizations and is heavily involved in UW's Plastic Surgery Training Program

Reviews

"Each chapter follow an outline that aims to be consistent throughout the volume. This format ensures that the topics are covered in an organized and comprehensive manner... The entire textbook is available in an accompanying online version. Additionally, there are certain parts of the chapters that are only available on-line including the historical perspective section, some figures, the complete references... In summary, Plastic Surgery, 3rd Edition, remains a pillar of any plastic surgeon's library. Volume Two is no exception and is a must have for any practicing plastic surgeon or trainee with an interest in aesthetic plastic surgery. Journal of Plastic, Reconstructive & Aesthetic Surgery (JPRAS), December 2013 "This is the latest edition of the multivolume plastic surgery textbook first edited by John M. Converse in 1964. Through the decades, this has remained the gold standard in plastic surgery textbooks. I have always had the most recent edition close to my desk and have used it as an initial reference when I have needed to review a topic. I will continue to use this edition in the same manner. Plastic surgeons at all stages in their careers can benefit from this book. The coverage of plastic surgery topics remains encyclopedic, and all of the authors are recognized experts in their subject areas.This edition demonstrates a number of differences from prior editions. The books themselves are slightly larger, and the majority of the artwork is in color, with a uniform style and is of high quality. This edition incorporates changes consistent with our digital age, while maintaining the excellent content that has been the hallmark of this book throughout the years." - Walter Lawrence, MPH, MD (University of Iowa Hospitals and Clinics) Doody 5 stars!