Retinoid Signaling Pathways, Volume 637, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Sections in this release include The chemistry and biochemistry of Vitamin A and its natural derivative, Biosynthesis of retinoic acids, Biodegration of retinoic acids mediated by retinoid binding proteins, Retinoic acid homeostasis, Cryo Electron Microscopy to study retinol update via the STRA6 receptor, Immuno-detection of retinoic acid synthesis enzymes in the brain, classical pathway of gene regulation by retinoids, Protein-protein interactions in the regulation of retinoid acid receptors activity, and much more.
Retinoid Signaling Pathways, Volume 637, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Sections in this release include The chemistry and biochemistry of Vitamin A and its natural derivative, Biosynthesis of retinoic acids, Biodegration of retinoic acids mediated by retinoid binding proteins, Retinoic acid homeostasis, Cryo Electron Microscopy to study retinol update via the STRA6 receptor, Immuno-detection of retinoic acid synthesis enzymes in the brain, classical pathway of gene regulation by retinoids, Protein-protein interactions in the regulation of retinoid acid receptors activity, and much more.
Vitamin A and its natural derivatives
Chris P.F. Redfern
Post-natal all-trans-retinoic acid biosynthesis
Joseph L. Napoli
Retinoid metabolism and functions mediated by retinoid
binding-proteins
Joseph L. Napoli and Hong Sik Yoo
Generation and isolation of recombinant retinoid oxidoreductase
complex
Mark K. Adams, Olga V. Belyaeva and Natalia Y. Kedishvili
Sample preparation for structural and functional analyses of the
STRA6 receptor for retinol-binding protein
Brianna K. Costabile, Youn-Kyung Kim, Yunting Chen, Oliver B.
Clarke, Loredana Quadro and Filippo Mancia
Use of fixatives for immunohistochemistry and their application for
detection of retinoic acid synthesizing enzymes in the central
nervous system
Azita Kouchmeshky and Peter McCaffery
Classical pathways of gene regulation by retinoids
Ehmke Pohl and Charles W.E. Tomlinson
Protein-protein interactions in the regulation of RAR–RXR
heterodimers transcriptional activity
Albane le Maire, Pierre Germain and William Bourguet
Natural ligands of RXR receptors
Patricia García, Paula Lorenzo and Angel R. de Lera
DNA recognition by retinoic acid nuclear receptors
Carole Peluso-Iltis, Judit Osz and Natacha Rochel
Noncanonical retinoic acid signaling
Jennifer Nhieu, Yu-Lung Lin and Li-Na Wei
Retinoic acid and microRNA
Lijun Wang, Atharva Piyush Rohatgi and Yu-Jui Yvonne Wan
Analysis of vitamin A and retinoids in biological matrices
Lindsay C. Czuba, Guo Zhong, King Yabut and Nina Isoherranen
Effects of vitamin A and retinoic acid on mouse embryonic stem
cells and their differentiating progeny
Mary Ann Asson-Batres and Christopher W. Norwood
Identifying vitamin A signaling by visualizing gene and protein
activity, and by biochemical isolation of vitamin A metabolites
Stephen R. Shannon, Jianshi Yu, Amy E. Defnet, Danika Bongfeldt,
Alexander R. Moise, Maureen A. Kane and Paul A. Trainor
Whole mount in situ hybridization and immunohistochemistry for
studying retinoic acid signaling in developing amphioxus
Matteo Bozzo, Simona Candiani and Michael Schubert
Design of synthetic retinoids
David R. Chisholm and Andrew Whiting
Application of human organotypic skin raft cultures for analysis of
retinoid metabolism, retinoic acid signaling, and screening of
bioactive rexinoids
Alla V. Klyuyeva, Kelli R. Goggans, Natalia Y. Kedishvili and Olga
V. Belyaeva
Tissue localization of retinoic acid receptor (RAR) active
drugs
Azita Kouchmeshky, Timothy Goodman, Andy Whiting and Peter
McCaffery
The development of methodologies for high-throughput retinoic acid
binding assays in drug discovery and beyond
Charles W.E. Tomlinson and Andrew Whiting
Using the human CYP26A1 gene promoter as a suitable tool for the
determination of RAR-mediated retinoid activity
Reza Zolfaghari, Floyd J. Mattie, Cheng-Hsin Wei, David R.
Chisholm, Andrew Whiting and A. Catharine Ross
Ehmke Pohl is at Durham University, Durham, UK
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