The need to expand expertise in cancer genetics beyond highly specialized genetics clinics is increasingly being recognized. In response, this practical book provides oncologists, specialist nurses, genetic counsellors, family doctors, and geneticists with comprehensive and easy-to-use guidelines on risk assessment and appropriate management.
The book focuses on common familial cancers such as breast, colorectal, ovary, prostate and melanoma, and separate chapters cover cancer predisposing syndromes such as neurofibromatosis, familial adenomatous polyposis and their management.
Professor Evans is secretary of the UK Cancer Genetics Group. He was chairman of the UK National Institute of Clinical Excellence guidelines on familial breast cancer, Chairman of the International Collaborative Group on Familial Breast and Ovarian Cancer and on the Editorial Board of Familial Cancer. Professor Friedman is Associate Editor of the journals Genetics in Medicine and Birth Defects Research: Clinical and Molecular Teratology, and a member of the editorial board of Clinical Genetics
Show moreThe need to expand expertise in cancer genetics beyond highly specialized genetics clinics is increasingly being recognized. In response, this practical book provides oncologists, specialist nurses, genetic counsellors, family doctors, and geneticists with comprehensive and easy-to-use guidelines on risk assessment and appropriate management.
The book focuses on common familial cancers such as breast, colorectal, ovary, prostate and melanoma, and separate chapters cover cancer predisposing syndromes such as neurofibromatosis, familial adenomatous polyposis and their management.
Professor Evans is secretary of the UK Cancer Genetics Group. He was chairman of the UK National Institute of Clinical Excellence guidelines on familial breast cancer, Chairman of the International Collaborative Group on Familial Breast and Ovarian Cancer and on the Editorial Board of Familial Cancer. Professor Friedman is Associate Editor of the journals Genetics in Medicine and Birth Defects Research: Clinical and Molecular Teratology, and a member of the editorial board of Clinical Genetics
Show moreIntroduction
1: Bronwyn Kerr: How to evaluate a family history
2: Fred Menko: Guidelines for referral in Europe
3: Susan Domchek & Barbara L Weber: Guidelines for genetic
counselling, testing and referral in North America
4: D Gareth Evans, Pål Moller & Bronwyn Kerr: Principles and
applications of gene testing for common cancers
Risk assessment of common malignancies
5: D Gareth Evans, Bronwyn Kerr & Fiona Lalloo: Risk estimation in
breast cancer
6: Fiona Lalloo: Risk estimation in colorectal cancer
7: D Gareth Evans: Risk estimation in ovarian cancer
8a: Pål Moller: Management of familial breast and ovarian cancer in
Europe
8b: Barbara C McGillivray: Management of familial breast and
ovarian cancer in North America
9: E Sheridan and R S Houlston: Management of familial adenomatous
polyposis and other inherited polyposis syndromes
10: H F A Vasen, J Burn, E Sheridan, R S Houlston & F Douglas:
Management of hereditary non-polyposis colorectal cancer
11: Sameer Jhavar & Rosalind Eeles: Management and risk assessment
of less common familial cancers
Inherited cancer syndromes
12: J M Friedman: The neurofibromatoses
13: Eamonn R Maher: von Hippel-Lindau disease
14: Fiona Lalloo: Multiple endocrine neoplasias
15: D Gareth Evans: Gorlin Syndrome
16: J M Birch: The Li-Frameni Syndrome
17: Fiona Lalloo & D Gareth Evans: Other tumour predisposing
syndromes
18: Patrick J Morrison: The ethical and insurance issues of cancer
genetics
Professor Evans is secretary of the UK Cancer Genetics Group. He
was chairman of the UK National Institute of Clinical Excellence
guidelines on familial breast cancer, Chairman of the International
Collaborative Group on Familial Breast and Ovarian Cancer and on
the Editorial Board of Familial Cancer.
Professor Friedman is Associate Editor of the journals Genetics in
Medicine and Birth Defects Research: Clinical and Molecular
Teratology, and a member of the editorial board of Clinical
Genetics
One of the commonest questions to a Clinical Genetics department is
'what do I do for this patient with a family history of cancer?'
While most departments have guidelines for referral, these are
intended to be for quick, easy-view reference. For those many
clinicians who would like a little more detail, Lalloo and
colleagues have produced this practical text with a worldwide list
of contributors...it is easy to find the information you need in
this book. Read it from cover to cover if it is valuable to your
training or practice (or if you just like the subject) and you will
have a comprehensive knowledge of what cancer genetics is about;
keep it for reference, dipping into the particular bit you need
from time to time, and your clinical genetics colleagues will be
very impressed with your knowledge.
*Ulster Medical Journal*
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